Primary clarithromycin resistance toHelicobacter pylori: Is this the main reason for triple therapy failure?
نویسندگان
چکیده
منابع مشابه
Effects of primary metronidazole and clarithromycin resistance to Helicobacter pylori on omeprazole, metronidazole, and clarithromycin triple-therapy regimen in a region with high rates of metronidazole resistance.
The aim of this study was to investigate the effect of metronidazole resistance (MtzR) and clarithromycin resistance (ClaR) on the eradication rate for omeprazole, clarithromycin, and metronidazole triple-therapy regimen and on the development of posttherapy drug resistance in a region of high rates of MtzR. One hundred ninety-six Helicobacter pylori isolates were recovered from patients with d...
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Tools for Practice articles in Canadian Family Physician are adapted from articles published twice monthly on the Alberta College of Family Physicians (ACFP) website, summarizing medical evidence with a focus on topical issues and practice-modifying information. The ACFP summaries and the series in Canadian Family Physician are coordinated by Dr G. Michael Allan, and the summaries are co-author...
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BACKGROUND In areas with high clarithromycin resistance, bismuth quadruple therapy (BQT) is recommended instead of clarithromycin triple therapy (CTT) as the first-line treatment for Helicobacter pylori eradication. METHODS Randomized clinical trials (RCTs) comparing BQT to CTT were identified through electronic and manual searches. A meta-analysis was performed to compare the efficacy and to...
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Helicobacter pylori resistance to metronidazole was detected in 107 (52.97%) of 202 strains. Twenty (9.85%) strains, 18 of them harboring 23S ribosomal DNA mutations, were resistant to clarithromycin. Metronidazole resistance was associated with female gender. Resistance to metronidazole and resistance to clarithromycin were associated. Increasing clarithromycin resistance rates were observed o...
متن کاملcomparison of azithromycin and clarithromycin triple therapy regimens for helicobacter pylori eradication in hemodialysis patients
background helicobacter pylori eradication with clarithromycin is more expensive than with azithromycin. objectives this study aimed to compare the effectiveness of these two antibiotics in eradicating h. pylori in hemodialysis (hd) patients. patients and methods this is a prospective, randomized, double-blinded clinical trial analysis of hd patients. patients who had dyspepsia and showed posit...
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ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Pathophysiology
سال: 2013
ISSN: 2150-5330
DOI: 10.4291/wjgp.v4.i3.43